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  Indian J Med Microbiol
 

Figure 5: Histopathological changes in liver of different groups. H and E, ×400. (a) Control group: liver tissue showed normal appearance of central vein with radiating cords of hepatocytes. (b) Ethylene glycol-treated group: disarrangement of hepatocyte cords, degeneration of hepatocytes (arrowhead), leukocyte infiltration, and congestion of hepatic sinusoids (*) were observed. Accumulations of eosinophilic material resembling crystals deposits (arrow) in the liver have been also observed. (c) In extract-treated rats, normal hepatic architecture was seen. Mild congestion of hepatic sinusoids and necrosis were noticed

Figure 5: Histopathological changes in liver of different groups. H and E, ×400. (a) Control group: liver tissue showed normal appearance of central vein with radiating cords of hepatocytes. (b) Ethylene glycol-treated group: disarrangement of hepatocyte cords, degeneration of hepatocytes (arrowhead), leukocyte infiltration, and congestion of hepatic sinusoids (*) were observed. Accumulations of eosinophilic material resembling crystals deposits (arrow) in the liver have been also observed. (c) In extract-treated rats, normal hepatic architecture was seen. Mild congestion of hepatic sinusoids and necrosis were noticed