Urological Science

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 29  |  Issue : 1  |  Page : 43--48

Oncological outcomes of high-risk prostate cancer patients between robot-assisted laparoscopic radical prostatectomy and laparoscopic radical prostatectomy in Taiwan


Chieh-Chun Liao, Yu-Chuan Lu, Huai-Chin Tai, Chung-Hsin Chen, Yeong-Shiau Pu, Chao-Yuan Huang 
 Department of Urology, National University Hospital, Taipei, Taiwan

Correspondence Address:
Chao-Yuan Huang
Department of Urology, National Taiwan University Hospital, No 7, Chun-Shan South Road, Taipei
Taiwan

Objective: To compare pathological and oncological outcomes between robotic-assisted laparoscopic radical prostatectomy (RaLRP) and laparoscopic radical prostatectomy (LRP) among high-risk prostate cancer patient in a tertiary center in Taiwan. Materials and methods: From November 2003 to October 2013, 129 high-risk prostate cancer patients receiving minimally-invasive radical prostatectomy were included. The Kaplan–Meier analysis was used for measuring biochemical recurrence-free survival (BFS). Multivariate logistic regression models and Cox proportional hazards regression models were used to determine predictors of positive surgical margin and BFS. Results: Among the 129 high-risk prostate cancer patients included, 80 (62%) patients received LRP and 49 (38%) patients received RaLRP. There was no significant difference of positive surgical margin and biochemical recurrence rate between RaLRP and LRP group (P = 0.802 and 0.292). Higher pathological T stage predicted an increased likelihood of positive margins (OR = 3.44, 95% CI [1.45, 8.18], P = 0.005). Higher initial PSA level (HR = 2.88, 95% CI [1.04, 7.94], P = 0.041) and positive surgical margin (HR = 2.55, 95% CI [1.20, 5.44], P = 0.015) were poor prognostic factors for BFS. Conclusion: RaLRP can be considered among high-risk prostate cancer in Asian people with comparable oncological outcomes to LRP. Higher pathological T stage was associated with increased likelihood of positive margins, patients with higher iPSA level and positive surgical margin had worsen biochemical recurrence-free survival.


How to cite this article:
Liao CC, Lu YC, Tai HC, Chen CH, Pu YS, Huang CY. Oncological outcomes of high-risk prostate cancer patients between robot-assisted laparoscopic radical prostatectomy and laparoscopic radical prostatectomy in Taiwan.Urol Sci 2018;29:43-48


How to cite this URL:
Liao CC, Lu YC, Tai HC, Chen CH, Pu YS, Huang CY. Oncological outcomes of high-risk prostate cancer patients between robot-assisted laparoscopic radical prostatectomy and laparoscopic radical prostatectomy in Taiwan. Urol Sci [serial online] 2018 [cited 2022 Sep 28 ];29:43-48
Available from: https://www.e-urol-sci.com/article.asp?issn=1879-5226;year=2018;volume=29;issue=1;spage=43;epage=48;aulast=Liao;type=0